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working principle of yinzhijiedukeli for swine fever

  • Diagnostics available for African Swine Fever virus

    2020-1-1 · • Over 180 scientists working on a range of viruses in specialist areas • CL2 and CL3 laboratory space • OIE CL4 containment facility (BSL3) • High-containment (BSL3) animal facilities Plowright building, Pirbright

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  • Classical Swine Fever - Generalized Conditions ...

    Classical swine fever is caused by a small, enveloped RNA virus in the genus Pestivirus of the family Flaviviridae. Classical swine fever virus (CSFV) is antigenically related to the other pestiviruses, mainly to bovine viral diarrhea virus (BVDV) of cattle and to border disease virus (BDV) of sheep. These viruses are highly prevalent in bovine and ovine populations and can infect pigs.

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  • African swine fever: a global view of the current ...

    2015-12-23 · African Swine Fever (ASF) is an important contagious haemorrhagic viral disease affecting swine whose notification is mandatory due to its high mortality rates and the great sanitary and socioeconomic impact it has on international trade in animal and swine products. This disease only affects porcine species, both wild and domestic, and produces a ...

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  • Expert knowledge elicitation on African Swine Fever

    2021-6-9 · An expert knowledge elicitation was conducted to address three tasks identified by EFSA's Animal Health and Welfare (AHAW) Panel: categorize outdoor farm types of pigs in EU MS according to the risk of African Swine Fever (ASF) introduction into these farms and the risk of ASF spread from these farms, rank biosecurity measures according to their potential to lower the risk of ASF introduction into …

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  • Management of classical swine fever and foot-and-

    2013-6-26 · as described above to a final working concentration of 0.10% w/v. The MAb, conjugate and chromogen-Figure 1. Principle of the IMB-ELISA for antigen detection. I: CSF virus antigen capture, II: specific detection by monoclonal antibody and III: chromogen-substrate colour development Figure 2. Colour range for test results; positive (bluest, score

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  • Classical Swine Fever - Generalized Conditions ...

    Classical swine fever is caused by a small, enveloped RNA virus in the genus Pestivirus of the family Flaviviridae. Classical swine fever virus (CSFV) is antigenically related to the other pestiviruses, mainly to bovine viral diarrhea virus (BVDV) of cattle and to border disease virus (BDV) of sheep. These viruses are highly prevalent in bovine and ovine populations and can infect pigs.

    Get Price
  • Epidemiological analyses of African swine fever in the ...

    Working principle This kit needs to be used with the AIGS Automatic Integrated Gene Detection System produced by HangZhou Lifereal Biotechnology Co., Ltd. The system uses real-time PCR detection technology, which integrates the automatic sample nucleic acid extraction/purification, nucleic acid amplification, fluorescence detection, and result analysis.

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  • Modeling and analysis of the symptomatic and

    A: Schematic representation of the spatial landscape of the simulations. African-swine-fever-infected animals enter from the right and continue to spread to the left. Once the simulated spatial spread reaches the Trigger-line, a prescribed control measure is applied to the blue zone.

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  • Big government: The fight against the African Swine

    2017-8-27 · Abstract Swine flu is an infectious disease which spreads very rapidly in the population. Infected droplets are expelled into the air by swine flu infected individuals through coughing and sneezing. This disease is transmitted to susceptible individuals by inhalation or ingestion of these infected droplets containing virus. In this paper, we

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  • The epidemic situation and its normalized prevention and ...

    2021-4-1 · Establish regional working mechanism for the investigation of epidemic situation covering all villages and farms • Implement the responsibility of investigation to each village and each farm, to ensure no omission. Report any abnormal situation in time. • Require the farms to report daily. For those who do not report according to the

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  • Entomological survey to study the possible

    2021-3-31 · Mechanical transmission of African swine fever virus (ASFV) has been investigated on few occasions, with Stomoxys calcitrans experimentally shown to transmit ASFV which was detected in various body parts for 3 days after infection. However, up to date, there is no field evidence demonstrating the presence of viral DNA in blood‐feeding arthropods.

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  • Management of classical swine fever and foot-and-

    2013-6-26 · for improved diagnosis of classical swine fever virus James Conlan1,2,3, Syseng Khounsy1, Manivanh Phruaravanh1, Vilaywan Soukvilai1, Chris Morrissy1,2, Axel Colling1,2, Stuart Blacksell4,5, Colin Wilks3 and Laurence Gleeson1,2,6 Abstract Classical swine fever (CSF) is a highly contagious viral disease of swine that causes major losses in all pig

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  • China - Peoples Republic of Multiple Outbreaks of African ...

    2018-8-22 · China reported a second and third outbreak of African Swine Fever, this time in the heart of China’s pig producing area. The second outbreak was identified on August 14, involving 30 dead pigs in a slaughterhouse in Zhengzhou City, Henan Province. The diseased pigs were traced back to a farm 1,500 miles away in Jiamusi City, Heilongjiang ...

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  • Virological diagnosis of African swine

    2013-4-1 · Diagnosis of African swine fever (ASF) is the identification of animals that are or have previously been infected with African swine fever virus (ASFV). A positive diagnosis involves the detection and identification of ASFV-specific antigens, antibodies or DNA in diagnostic samples taken from pigs using virus isolation, serological or molecular ...

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  • Principles of ventilation - Articles - pig333, pig to pork ...

    2009-3-18 · African Swine Fever. All the information about ASF in China, Belgium, Vietnam, Poland, Romania, Bulgaria, Russia, Mongolia, Hungary, Ukraine, Latvia... . Diseases manual. Description of the most important diseases and conditions in pigs. Atlas of pathology. Images of major swine diseases. E-diagnostics. Pig disease diagnostic tool. Pig glossary

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  • Risk of African swine fever virus introduction into the ...

    2019-10-8 · African swine fever causes substantial economic losses in the swine industry in affected countries. Traditionally confined to Africa with only occasional incursions into other regions, ASF began ...

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  • Modeling and analysis of the symptomatic and

    2017-8-27 · return with fever and worse cough, fever with a rash, being unable to eat, having no tears when crying (CDC 2016). There are several mathematical models to describe and analyze the transmission dynamics of influenza. In Sharomi et al. (2011), authors presented a deterministic model for the transmission dynamics of swine influenza (H1N1) in

    Get Price
  • Basics of Biosensors and Nanobiosensors p. 1 Biosensor

    2020-10-19 · Biosensors for Swine Influenza Viruses p. 311 Introduction p. 311 Diagnostic Methods for Swine Influenza Virus and Their Limitations p. 312 Nanomaterial-Based Sensors p. 313 Applications of Carbon-Based Nanomaterials p. 313 Gold Nanoparticle-Based Biosensing p. 315 Gold Nanoparticle-Based Localized Surface Plasmon Resonance Sensors p. 315

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  • Structure and operating principle of electric fans

    Propeller. Fan motor. Fan control bugs by board or by switch. Motor turns right to left. (Function) switch for the engine to turn right and left. Capacitor (capacitor for fan motor) Power cord. Remote control (whether there are any or not) This is the whole structure of a most common electric fan.

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  • Sampling strategy of swine disease surveillance and how

    Swine disease surveillance 15:30-15:50 OIE Principle of Swine Disease Surveillance: type of surveillance and critical elements Dr Yin Li hina Animal Health and Epidemiology enter(AHE ) 15:50-16:10 Practice of Swine Disease Surveillance: Role of the MOA and Laboratory in disease surveillance, skills and information required at

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  • Analysis of the strategy developed for control of the ...

    African swine fever (ASF) is a highly contagious and deadly disease in domestic and feral pigs ... In principle, the strategy present one declared intention and ... Hence, the matters associated with the working conditions of the two rendering plants, the collection and disposal of the carcasses, the slaughterhouse byproducts, the ...

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  • Frontiers | Evidence-Based African Swine Fever Policies ...

    2021-3-24 · African swine fever (ASF) is one of the most threatening diseases for the pig farming sector worldwide. Prevention, control and eradication remain a challenge, especially in the absence of an effective vaccine or cure and despite the relatively low contagiousness of this pathogen in contrast to Classical Swine Fever or Foot and Mouth disease, for example.

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  • THE IMPACT OF THE AFRICAN SWINE FEVER OUTBREAK

    2021-5-18 · African Swine Fever (ASF) is a highly contagious viral disease affecting domestic and wild pigs. It does not affect humans or other species. Symptoms include fever, loss of appetite, lack of energy, miscarriages, and internal bleeding. Severe strains of the virus are generally fatal.

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  • August 2015 virotype ASFV PCR Kit Handbook

    from African swine fever virus (ASFV) in serum, plasma, EDTA-blood, tissue, and swab samples from pigs and wild boar. The kit is approved by the Friedrich-Loeffler-Institut and licensed in accordance with § 11 (2) of the German Animal Health Act (FLI-B 670) for use in Germany for veterinary diagnostic procedures. For veterinary use only.

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  • NATIONAL ANIMAL HEALTH LABORATORY NETWORK

    2018-10-30 · Classical Swine Fever Chronic Wasting Disease Foot and Mouth Disease Influenza A Virus -Avian Influenza A Virus -Swine Infectious Salmon Anemia Newcastle Disease Pseudorabies Scrapie Spring Viremia of Carp Viral Hemorrhagic Septicemia Vesicular Stomatitis Virus. Founding Principle: Competency of Lab Personnel

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  • Sensing the classical swine fever virus with molecularly ...

    2020-6-6 · Classical swine fever (CSF), also known as hog cholera, is a highly contagious and fatal viral disease in pigs caused by the classical swine fever virus (CSFV). The World Organization for Animal Health (OIE) classifies CSF as a specific hazard of importance in international trade (OIE, 2020). Any outbreak has to be reported, because it can ...

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  • ASF: the biggest threat to the world’s swine industry ...

    2021-3-19 · Working together as the answer to eradicate ASFv. The words ‘viruses’ and ‘cooperation’ both form key concepts through the life and career of professor José Manuel Sánchez-Vizcaíno. The 2 concepts come together in the latest project he has embarked on: being the coordinator of a European consortium to once and for all eradicate ...

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  • Working together as the answer to eradicate ASFv -

    2020-12-21 · African Swine Fever (ASF) is an emerging infectious disease caused by a DNA virus that is lethal for many pig species, but is harmless to people and other animals (FAO, 2020). Transmission occurs through direct contact, indirectly via vectors, such as Ornithodoros ticks (Golnar et al., 2019 ), or through consumption of infected carcasses or ...

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  • European Communities EUROPEAN PARLIAMENT

    2015-4-17 · classical swine fever. Classical swine fever is a particularly virulent and contagious disease which is very rapidly transmitted and leads to high mortality in the pig herd or, in less acute cases, 2 fall in the profitability of pig farming and great economic losses. Swine fever has been eliminated in the three new Member States.

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  • Development of new vaccine against Classical Swine

    2021-3-31 · Mechanical transmission of African swine fever virus (ASFV) has been investigated on few occasions, with Stomoxys calcitrans experimentally shown to transmit ASFV which was detected in various body parts for 3 days after infection. However, up to date, there is no field evidence demonstrating the presence of viral DNA in blood‐feeding arthropods.

    Get Price
  • Entomological survey to study the possible

    2021-5-18 · African Swine Fever (ASF) is a highly contagious viral disease affecting domestic and wild pigs. It does not affect humans or other species. Symptoms include fever, loss of appetite, lack of energy, miscarriages, and internal bleeding. Severe strains of the virus are generally fatal.

    Get Price
  • THE IMPACT OF THE AFRICAN SWINE FEVER OUTBREAK

    Background. The emergence of Classical Swine Fever (CSF) within a wild boar population is a highly undesirable event. This is mainly due to the potential transmissibility of the infectious agent from wild boar into domestic pig populations [1–3].Also, strict movement regulations affecting domestic pig holdings are implemented for the holdings in the restriction zone around a CSF outbreak ...

    Get Price
  • Hunters’ acceptability of the surveillance system and ...

    Classical Swine Fever Virus Antibody (IgG) ELISA Kit. Instructions. Code. CSB-E12765p. Size. 96T,5×96T,10×96T. Trial Size.

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  • Classical Swine Fever Virus Antibody(IgG) ELISA Kit -

    The mission of the Swine Health Information Center, launched in 2015 with Pork Checkoff funding, is to protect and enhance the health of the United States swine herd through coordinated global disease monitoring, targeted research investments that minimize the impact of future disease threats, and analysis of swine health data.

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  • Swine Health Information Center

    2017-8-27 · return with fever and worse cough, fever with a rash, being unable to eat, having no tears when crying (CDC 2016). There are several mathematical models to describe and analyze the transmission dynamics of influenza. In Sharomi et al. (2011), authors presented a deterministic model for the transmission dynamics of swine influenza (H1N1) in

    Get Price
  • Modeling and analysis of the symptomatic and

    External expert in the ASF working group, EFSA 2018-2019. Member of the Danish expert groups on foot and mouth disease and on swine fever. Possible conflicts of interest: As senior advisor, I am deeply involved in the research based public sector services. My previous work in the swine industry has given the benefits of a continued fruitfull ...

    Get Price
  • European Communities EUROPEAN PARLIAMENT

    2015-4-17 · classical swine fever. Classical swine fever is a particularly virulent and contagious disease which is very rapidly transmitted and leads to high mortality in the pig herd or, in less acute cases, 2 fall in the profitability of pig farming and great economic losses. Swine fever has been eliminated in the three new Member States.

    Get Price
  • Development of new vaccine against Classical Swine

    2020-6-6 · Classical swine fever (CSF), also known as hog cholera, is a highly contagious and fatal viral disease in pigs caused by the classical swine fever virus (CSFV). The World Organization for Animal Health (OIE) classifies CSF as a specific hazard of importance in international trade (OIE, 2020). Any outbreak has to be reported, because it can ...

    Get Price
  • Sensing the classical swine fever virus with molecularly ...

    Swine disease surveillance 15:30-15:50 OIE Principle of Swine Disease Surveillance: type of surveillance and critical elements Dr Yin Li hina Animal Health and Epidemiology enter(AHE ) 15:50-16:10 Practice of Swine Disease Surveillance: Role of the MOA and Laboratory in disease surveillance, skills and information required at

    Get Price
  • Sampling strategy of swine disease surveillance and how

    Understanding African swine fever virus (ASFV) transmission is essential for strategies to minimize virus spread during an outbreak. ASFV can survive for extended time periods in animal products, carcasses, and the environment. While ASFV genome was found in the environment around infected farms, data on the virus survival in soil are scarce.

    Get Price
  • Stability of African Swine Fever Virus in Soil and

    2021-3-23 · African swine fever (ASF), infection with tilapia lake virus and infection with white spot syndrome in many parts of Africa, Europe, Asia, the Americas and the Middle East demonstrates the weakness of Veterinary Services to provide effective control methods and treatments, especially where they are needed most: in poor, remote communities. All this

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  • ASF: the biggest threat to the world’s swine industry ...

    2017-8-15 · Manual on African swine fever for pig producers. M. 2000. La maladie de Newcastle dans les élevages avicoles villageois. M. Plan continental para la erradicación de la peste porcina clásica de las américas. M . Recognizing african swine fever: a field manual. M . 1999. Manual on livestock disease surveillance and information systems. M

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  • European Communities EUROPEAN PARLIAMENT

    2015-4-17 · classical swine fever. Classical swine fever is a particularly virulent and contagious disease which is very rapidly transmitted and leads to high mortality in the pig herd or, in less acute cases, 2 fall in the profitability of pig farming and great economic losses. Swine fever has been eliminated in the three new Member States.

    Get Price
  • ASF: the biggest threat to the world’s swine industry ...

    Swine disease surveillance 15:30-15:50 OIE Principle of Swine Disease Surveillance: type of surveillance and critical elements Dr Yin Li hina Animal Health and Epidemiology enter(AHE ) 15:50-16:10 Practice of Swine Disease Surveillance: Role of the MOA and Laboratory in disease surveillance, skills and information required at

    Get Price
  • Sampling strategy of swine disease surveillance and how

    Understanding African swine fever virus (ASFV) transmission is essential for strategies to minimize virus spread during an outbreak. ASFV can survive for extended time periods in animal products, carcasses, and the environment. While ASFV genome was found in the environment around infected farms, data on the virus survival in soil are scarce.

    Get Price
  • Stability of African Swine Fever Virus in Soil and

    Extracts from SPS Committee meeting summary reports In July 2015, the European Union raised concerns about China's bans due to African Swine Fever (ASF) and indicated that the vast majority of EU trading partners did not take any import measures against the European Union on African Swine Fever (ASF) grounds because they fully trusted the strict EU control system.

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  • Specific Trade Concerns - Sanitary and

    Test principle: Blocking enzymatic assay: No. of tests: 192: Min no. of samples: 64: Max no. of samples: 192: Format: 2 microtiter plates with 192 wells: Detection: Specific antibodies to African Swine Fever Virus in porcine sera samples: Shelf Life (months) 18: Storage: 2–8°C

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  • Responsible Imports | Pipestone

    External expert in the ASF working group, EFSA 2018-2019. Member of the Danish expert groups on foot and mouth disease and on swine fever. Possible conflicts of interest: As senior advisor, I am deeply involved in the research based public sector services. My previous work in the swine industry has given the benefits of a continued fruitfull ...

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  • ASSESSING SOCIAL, ECOLOGICAL AND ECONOMIC

    2014-11-10 · potential zoonotic disease in free-ranging swine. Socio-economic consequences . Several examples illustrate the devastating economic effects of classical (CSF) and African swine fever (ASF) spilling over from wild boar to domestic pigs. the 1990’s From until the …

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  • Hunters’ acceptability of the surveillance system and ...

    Background. The emergence of Classical Swine Fever (CSF) within a wild boar population is a highly undesirable event. This is mainly due to the potential transmissibility of the infectious agent from wild boar into domestic pig populations [1–3].Also, strict movement regulations affecting domestic pig holdings are implemented for the holdings in the restriction zone around a CSF outbreak ...

    Get Price
  • Swine fever emergency taxing available human

    2014-9-2 · The government approved in principle the allocation of additional funding worth about €600,000 to the Food and Veterinary Service (PVD) for expanding its crew of veterinary health inspectors currently deployed in the African swine fever (ASF) state-of-emergency zones in eastern Latgale and northern Vidzeme provinces, reported business portal Nozare.lv Tuesday.

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  • Can China learn from Russia and save its pigs from

    2018-12-7 · China slaughters 38,000 pigs to stop spread of swine fever. Larger operations, like Miratorg, typically grow their own animal feed and carefully manage raw materials allowed on farms. Russia’s ...

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  • PigProgress - The Fortress Farm – what does it look

    External expert in the ASF working group, EFSA 2018-2019. Member of the Danish expert groups on foot and mouth disease and on swine fever. Possible conflicts of interest: As senior advisor, I am deeply involved in the research based public sector services. My previous work in the swine industry has given the benefits of a continued fruitfull ...

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  • The application of the Keshe Foundation GANS

    2018-8-28 · PCV2 VLP Vaccines Manufactured using Baculovirus Expression Systems. August 28, 2018. By Dr. Jeffrey W. Hall, Pharmgate Research Scientist. The family of viruses known as “baculovirus” infects invertebrates, with moth larvae serving as the most common host. Foundational research dating to the late 1950’s set the stage for the development ...

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  • Anette Ella Boklund - Employees at IVH

    2020-9-10 · The case concerned a wild boar, not a farm animal, found near the German-Polish border in the eastern state of Brandenburg, German agriculture minister Julia Kloeckner said on Thursday.

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  • PCV2 VLP Vaccines Manufactured using Baculovirus ...

    2016-1-28 · Organic Rankine cycle (ORC) is a promising way for low temperature waste heat utilization. The performance of an ORC system is strongly related to the working fluid. Therefore, working fluid selection is a primary task in customizing an ORC to a specific background process for waste heat recovery. In refineries, there are huge amounts of waste heat, in which some waste heat streams ...

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  • Development of new vaccine against Classical Swine

    Since then, every time a new virus has come into circulation, this topic re-emerged, including in 2009 with the swine flu pandemic which is estimated to have infected about 1 billion people around the globe. Now, with the spread of the new coronavirus and COVID-19, fever screening systems, became of …

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  • Non-contact Body Temperature Measurement -

    2019-11-21 · African swine fever continues to cause major concerns within the hunting community Brussels, 21 November 2019 – The hunting community is becoming increasingly concerned about new cases of African swine fever (ASF) in western Poland, not far from the German border, and in southern Bulgaria, very close to the Greek border.

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  • African swine fever continues to cause major concerns ...

    2019-12-19 · African swine fever kills nearly 30,000 pigs in Indonesia. Authorities in Indonesia's North Sumatra are burying infected pigs in deep pits. Tens of thousands of pigs have died from African swine ...

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  • African swine fever kills nearly 30,000 pigs in

    2019-4-18 · Dr. John Korslund updated the committee on the recent African swine fever (ASF) outbreak in the Republic of Georgia. He and three other APHIS employees were detailed to the region to investigate the outbreak and offer recommendations for control and recovery. He described swine production in Georgia as composed of “backyard” type operations.

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  • REPORT OF THE COMMITTEE ON TRANSMISSIBLE

    African Swine Fever - Latest developments; African Swine Fever - Latest developments. ... The Commission immediately decided to apply the WTO regionalisation principle, in line with the OIE international standards. ... there were several working hypothesis being assessed. The most likely hypothesis appears to be linked with the crossing of the ...

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  • African Swine Fever - Latest developments

    Suvaxyn CSF Marker is used to protect pigs against outbreaks of classical swine fever, a very severe and highly contagious viral disease of both wild and domestic pigs. This disease causes fever, skin lesions, convulsions and often leads to death of the animals. The vaccine is given to pigs from seven weeks of age as a single injection into the muscle.

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  • The Yangxiang project - Articles - pig333, pig to

    2018-6-29 · African Swine fever first was discovered in European Union in 2014, entering it from Belarus. Since then, it has spread to Poland, Latvia, Estonia, Czech Republic, Hungary and Romania. It is widely spread in Ukraine, Russia with some cases in Moldova. It is a deadly virus that affects domestic

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  • Suvaxyn CSF Marker | European Medicines Agency

    African horse sickness. Evolution of the disease within the EU. Lithuania made in January 2014 the first notification of ASF cases in wild boar, and Poland followed in February 2014.In June and September 2014, Latvia and Estonia respectively also reported ASF.A summary report of the ASF findings in the EU, in both domestic pigs and in wild boar is available.

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  • African Swine Fever - Latest developments

    African Swine Fever - Latest developments; African Swine Fever - Latest developments. ... The Commission immediately decided to apply the WTO regionalisation principle, in line with the OIE international standards. ... there were several working hypothesis being assessed. The most likely hypothesis appears to be linked with the crossing of the ...

    Get Price
  • African Swine Fever - Latest developments

    African horse sickness. Evolution of the disease within the EU. Lithuania made in January 2014 the first notification of ASF cases in wild boar, and Poland followed in February 2014.In June and September 2014, Latvia and Estonia respectively also reported ASF.A summary report of the ASF findings in the EU, in both domestic pigs and in wild boar is available.

    Get Price
  • African swine fever continues to cause major concerns ...

    2019-11-21 · African swine fever continues to cause major concerns within the hunting community Brussels, 21 November 2019 – The hunting community is becoming increasingly concerned about new cases of African swine fever (ASF) in western Poland, not far from the German border, and in southern Bulgaria, very close to the Greek border.

    Get Price
  • EU Commission: UECBV committed to fight African

    2018-6-29 · African Swine fever first was discovered in European Union in 2014, entering it from Belarus. Since then, it has spread to Poland, Latvia, Estonia, Czech Republic, Hungary and Romania. It is widely spread in Ukraine, Russia with some cases in Moldova. It is a deadly virus that affects domestic

    Get Price
  • DEEP CONCERNS EXPRESSED BY STAKEHOLDERS

    2019-4-18 · Dr. John Korslund updated the committee on the recent African swine fever (ASF) outbreak in the Republic of Georgia. He and three other APHIS employees were detailed to the region to investigate the outbreak and offer recommendations for control and recovery. He described swine production in Georgia as composed of “backyard” type operations.

    Get Price
  • REPORT OF THE COMMITTEE ON TRANSMISSIBLE

    2019-8-29 · Feed manufacturers and farmers are spearheading efforts to improve biosecurity amid African swine fever (ASF) concerns, as preventative nutrition and vaccine innovation also take the spotlight. ASF, a viral disease that affects porcine species, has plagued numerous markets in recent years, most notably China, the world’s largest pork consumer ...

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  • EU aligns biosecurity measures to contain ASF -

    2020-9-10 · Germany confirmed on Thursday that African swine fever (ASF) had been found in a dead wild boar near its border with Poland, threatening pork exports to China from Europe's biggest pork producer, which were worth 1.2 billion (921.23 million pounds) last year. The disease is not dangerous to humans but it is fatal to pigs and a massive outbreak in China, the world's biggest pork producer, …

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  • Swine fever found in Germany putting pork exports

    2010-3-10 · Relapsing fever was the term coined to describe the clinical disease following an outbreak of infection in Edinburgh during 1843–8, however, the aetiology of this infection remained obscure until the meticulous studies of Otto Obermeier in 1873 whist working in the Berlin Charité hospital (Birkhaug 1942). Despite intensive attempts to ...

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