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2021-6-28 · Povidone-Iodine Solution 10% Indications. A topical antiseptic to aid in the prevention of infection. Film-forming, virtually non-irritating and non-staining to skin, hair and natural fabrics. Directions For Use. Apply full strength as often as needed. Wet area thoroughly to ensure complete coverage and penetration but avoid “pooling.”
Get Price2007-2-1 · Animals were anesthetized and intravitreally injected with 0.1 mL of 50, 100, 200, or 400 micrograms (microg) of PVP-I in 1 eye, and with saline in the other. The animals were examined at days 1, 7, and 14, using indirect ophthalmoscopy and slit-lamp biomicroscopy; electroretinography (ERG) was performed before treatment and prior to euthanization.
Get PricePovidone-iodine (6·0-7·5 mg available iodine/kg body weight) significantly reduced the mortality of both mice (P<0·001) and rats (P<0.01) in treated animals compared to matched controls. The mortality rate of rats treated with povidone-iodine was significantly less than those treated with noxythiolin ( P <0·01).
Get PriceTwo experimental studies were carried out upon dogs to clarify the efficacy of peritoneal povidone-iodine lavage in peritonitis. With an experimental model of peritonitis which closely resembles the clinical situation, we found that peritoneal lavage with povidone-iodine was not more effective than other lavage regimens in decreasing bacterial colony counts and was associated with an early 100 per cent mortality.
Get Price2018-11-27 · The swamp eel (Monopterus albus) is an important commercial farmed fish species in China. However, it is susceptible to Aeromonas hydrophila infections, resulting in high mortality and considerable economic loss. Povidone-iodine (PVP-I) is a widely used chemical disinfectant in aquaculture, which can decrease the occurrence of diseases
Get PriceBackground: Intrauterine infusions have been widely used for the treatment of endometritis in the mare. Nevertheless, their consequences on endocrine and endometrial molecular aspects are unknown. We studied the effect of a 1% povidone-iodine solution intrauterine infusion on progesterone levels, endometrial histology and estrogen (ERα) and progesterone (PR) receptor distribution by ...
Get PricePovidone-iodine (Betadine) is a complex of the potent bactericidal agent iodine and the carrier molecule povidone. On contact with tissues, the carrier complex slowly releases free iodine. Gradual release decreases tissue irritation and reduces potential toxicity while preserving the agent’s germicidal activity.
Get PriceComplexing iodine with povidone (polyvinylpyrrolidone) or surfactants significantly limits the quantity of free iodine. Reduction of the free iodine level eliminates the adverse properties of staining, instability, and irritation and also alters bactericidal activity. Addition of detergents to creat …
Get PricePovidone-iodine (6·0-7·5 mg available iodine/kg body weight) significantly reduced the mortality of both mice (P<0·001) and rats (P<0.01) in treated animals compared to matched controls. The mortality rate of rats treated with povidone-iodine was significantly less than those treated with noxythiolin (P<0·01).
Get Price2012-7-9 · Povidone‐iodine (PI), a compound of iodine and polyvinylpyrrolidone, is a common anti microbial agent and has been used as a surgical scrub or a skin cleanser in various forms. Although PI has a strong anti microbial effect, the use of PI as a topical agent was limited because of …
Get Priceanimals, in the form of the admixture of Povidone-Iodine (10% available iodine ) into the feed in dosages of between 75 and 750 mg Povidone-Iodine per day and kg body weight for up to 12 weeks. After the Povidone-Iodine addition was stopped, only the practically completely reversible and dose-dependent rises in PBI (protein-bound
Get Price2010-12-16 · Intrauterine infusions have been widely used for the treatment of endometritis in the mare. Nevertheless, their consequences on endocrine and endometrial molecular aspects are unknown. We studied the effect of a 1% povidone-iodine solution intrauterine infusion on progesterone levels, endometrial histology and estrogen (ERα) and progesterone (PR) receptor distribution by …
Get Price2019-3-1 · Povidone-iodine is currently available in concentrations of 5, 7.5, and 10% weight/volume (w/v). One study found that the ototoxic effects were significantly greater in animals that had 10% povidone-iodine applied to the middle ear ( Ozkiris et al., 2013 ). The solvents contained in the antiseptic may also cause ototoxicity.
Get Price2019-11-12 · Minims Povidone Iodine 5% w/v eye drops, solution can be used during pregnancy. In pregnant or breastfeeding women an alternative form of antisepsis should be considered if multiple repeat injections requiring conjunctival and periorbital application are anticipated.
Get Price2017-1-1 · 3. Basic science of Povidone-iodine. Povidone-iodine is an antiseptic solution consisting of polyvinylpyrrolidone and 1% available iodine. 16 Iodine has great bactericidal activity but has very low solubility in aqueous environments. 19 To combat this, it is conjugated to polyvinylpyrrolidone, which is hydrophilic and able to deliver free iodine directly to the cell surface. 20, 21
Get Price2020-11-20 · Label: BARRIER WOUND CARE WITH PAIN RELIEF- povidone-iodine, lidocaine, and alcohol solution. NDC Code (s): 51072-036-01, 51072-036-16. Packager: Aurora Pharmaceutical, Inc. DISCLAIMER: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA.
Get Price2021-6-28 · Povidone-Iodine Solution 10% Indications. A topical antiseptic to aid in the prevention of infection. Film-forming, virtually non-irritating and non-staining to skin, hair and natural fabrics. Directions For Use. Apply full strength as often as needed. Wet area thoroughly to ensure complete coverage and penetration but avoid “pooling.”
Get Price1996-1-1 · The efficacy of either povidone-iodine (Betadine) or dichloroxylenol (Septocid) intrauterine infusions on the treatment of endometritis and/or cervicitis in cows was examined. One hundred and twelve repeat-breeder Holstein cows (aged 3-7 years) were selected for this study. Rectal and vaginal examinations were applied to detect the signs of ...
Get Price2012-7-9 · Povidone‐iodine (PI), a compound of iodine and polyvinylpyrrolidone, is a common anti microbial agent and has been used as a surgical scrub or a skin cleanser in various forms. Although PI has a strong anti microbial effect, the use of PI as a topical agent was limited because of …
Get Price2007-3-6 · Purpose: Firstly, the aim of this study was to determine the maximally tolerated dose of intravitreally injected povidone-iodine (PVP-I).A second aim was to test the efficacy of PVP-I on rabbit eyes infected intravitreally with Staphylococcus epidermidis.. Methods: Phase I of the study used 16 New Zealand albino rabbits, divided into 4 groups (n = 4 each).
Get Priceanimals, in the form of the admixture of Povidone-Iodine (10% available iodine ) into the feed in dosages of between 75 and 750 mg Povidone-Iodine per day and kg body weight for up to 12 weeks. After the Povidone-Iodine addition was stopped, only the practically completely reversible and dose-dependent rises in PBI (protein-bound
Get Price2020-7-21 · All patients with CUH were treated with 0.5% povidone iodine for pelvicalyceal system instillation, which was given at 12-h intervals for 3 days. Only 1 patient experienced recurrent gross hematuria, after 24 months postoperatively. The overall success rate, defined as resolution of gross hematuria after povidone iodine sclerotherapy, was 95%.
Get Price2003-2-1 · Povidone-iodine stock solution is 10%, comprising 90% water, 8.5% povidone-iodine, 1% available iodine, and iodide. 3 Previous studies have shown that 5% povidone-iodine effectively decreases the bacterial flora of the ocular surface and adnexae, 9– 12 and thus theoretically decreases the risk of endophthalmitis, while other large studies ...
Get PriceNowadays many products are available to combat infections and thus to promote wound healing. Iodine is one of these products, but reports are conflicting as to the effectiveness and adverse effects of iodine in the treatment of wounds. A systematic review was performed of 27 randomised clinical tria …
Get Price2020-11-20 · Label: BARRIER WOUND CARE WITH PAIN RELIEF- povidone-iodine, lidocaine, and alcohol solution. NDC Code (s): 51072-036-01, 51072-036-16. Packager: Aurora Pharmaceutical, Inc. DISCLAIMER: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA.
Get Price2020-4-10 · Nigeria) and povidone iodine 10% (Wosan ® Solution, Jawa International Ltd, Nigeria). All experimental animals were housed in the state veterinary clinic and surgery kennels, Agbor, Delta State, Nigeria. The experimental animals were maintained on a standard diet once daily with water ad libitum. The animals were stabilized for two weeks
Get Pricepovidone iodine solution and sterile 0.9% saline. In cases of corneal perforation, only sterile saline was used. Any ne-crotic corneal tissue was resected with corneal scissors, and fibrin protruding through the perforation site was trimmed. A viscoelastic solution (D-Rhexx, Dioptrix) was used
Get Price2000-5-29 · Purpose: To compare the antibacterial effect of povidone-iodine (PI) with that of ofloxacin in an experimental model of bacterial keratitis.Methods: Staphyloccocal keratitis was induced in 21 eyes of Dutch Belted rabbits by intrastromal inoculation of approximately 280 organisms of Staphylococcus aureus. Six hours later, the animals were divided in four groups treated topically with saline 0.9 ...
Get Price2011-2-1 · Povidone-iodine. Some surgeons recommend povidone-iodine solutions as cleaning agents.5 Dilute iodine solutions have been found to have no benefit over sterile saline solution as a cleansing agent for fixation element-skin interfaces in people.13 Cytotoxicity to canine fibroblasts has been documented when povidone-iodine concentrations exceed 0 ...
Get PriceDERMAL BETADINE 10 PERCENT, solution for local application, bottle of 125 ml. Povidone iodine. Updated on 11/08/2019. i. The Claude Bernard Base (BCB) is a database of drugs and health products that aims to help health professionals in their daily practice of prescribing, dispensing and dispensing and provide comprehensive information to the general public .
Get Price1986-7-1 · Three concentrations of povidone‐iodine (0.1% w/v, 0.2% w/v, 0.5% w/v) and one concentration of chlorhexidine (0.5% w/v) were selected as antimicrobial joint lavage solutions. Through‐and‐through joint lavage was performed with one of these antimicrobial solutions on a tarsocrural joint of 12 horses. The contralateral tarsocrural joints (control limbs) were lavaged with a …
Get PriceThus a 15% by weight, aqueous solution of povidone K-30 will require an amount of iodine of from 0.1% to 20% by weight of iodine based on the povidone content and from 0.01 part to 100 parts by weight of iodine ion, per part of iodide, to achieve the desired protective action.
Get Price2017-3-7 · Ringer's solution and hypochlorous acid/sodium hypochlorite showed significantly (P < 0·05) lower rates than those treated with sterile water, with a bacterial count of 6·78 ± 0·53 and 6·75 ± 0·40 log CFU/g, respectively. Sterile water-treated wounds showed a higher bacterial count, 7·61 ± 0·54 log CFU/g, on day 6, compared to ...
Get Price2021-6-28 · Povidone-Iodine Solution 10% Indications. A topical antiseptic to aid in the prevention of infection. Film-forming, virtually non-irritating and non-staining to skin, hair and natural fabrics. Directions For Use. Apply full strength as often as needed. Wet area thoroughly to ensure complete coverage and penetration but avoid “pooling.”
Get Price2020-4-10 · Nigeria) and povidone iodine 10% (Wosan ® Solution, Jawa International Ltd, Nigeria). All experimental animals were housed in the state veterinary clinic and surgery kennels, Agbor, Delta State, Nigeria. The experimental animals were maintained on a standard diet once daily with water ad libitum. The animals were stabilized for two weeks
Get PriceThe povidone-iodine is used in therapeutically effective amounts ranging up to about 25% by weight of the polymeric film, and preferably in amounts ranging from about 0.01 to 10% by weight of the polymeric film. Povidone-iodine is known to kill gram-positive and gram-negative bacteria, as wells as fungi, viruses, protozoa, and yeast.
Get Price2020-1-30 · consisting of six animals as follows: group I, le untreated andconsideredascontrol,groupII,whichservedasnegative control (ointment base treated), group III, which served as standard and was treated with %(w/w) povidone iodine ointment USP (Intadine), groups IV and V which were treated with % and %(w/w) ointments of extract, respec-tively.
Get PriceCompared to iodine and potassium iodide tablets, J.CROW'S Lugol's Solution offers big savings. Approximately 1200 vertical drops per 2 oz. container. To use as a water purifier add 3-6 drops per liter of water. Made from premium ingredients, the iodine used in J.CROW'S Lugol's Solution is derived from mined crystals from 320 million year old ...
Get PriceABSTRACT. PURPOSE: To evaluate the effectiveness of the use of the povidone-iodine (PVI) added to the liquid of wash of the peritoneal cavity in the reduction of bacterial absorption and in the remainder non-phagocyted bacteria in the circulating blood of rat. METHODS: Thirty four Wistar females rats were used, distributed in the following groups: A (n=10), non-treated; B (n=9), wash of the ...
Get Price(P<01)but was ineffective in rats. Povidone-iodine (6-0-7-5 mgavailable iodine/kg body weight) signifi-cantly reduced the mortality ofboth mice (P<0001) and rats (P<0.01) in treated animals compared to matched controls. The mortality rate ofrats treated with povidone-iodine was significantly less than those treated with noxythiolin (P<001 ...
Get Price2020-4-10 · Nigeria) and povidone iodine 10% (Wosan ® Solution, Jawa International Ltd, Nigeria). All experimental animals were housed in the state veterinary clinic and surgery kennels, Agbor, Delta State, Nigeria. The experimental animals were maintained on a standard diet once daily with water ad libitum. The animals were stabilized for two weeks
Get Price2020-9-1 · We evaluated the toxicity of 5% (w/v) povidone-iodine (PI) applied to the ocular surface of rabbits. Twenty-three white rabbits were divided into four groups; these were a control group and three study groups in which the ocular surface was exposed to PI for different times. In control group, one drop of phosphate-buffered saline (PBS) was applied once for 10 min.
Get Price2020-4-17 · Background: Complexes of iodine (povidone-iodine and cadexomers) are among the most important antiseptics used in clinical and veterinary medicines. However, high local irritation activity and systemic toxicity limits their oral administration. The purpose of the study was to compare the effect of a new complex of iodine (PA, potentiator of anticancer antibiotics), in which iodine is ...
Get Price2011-2-1 · Povidone-iodine. Some surgeons recommend povidone-iodine solutions as cleaning agents.5 Dilute iodine solutions have been found to have no benefit over sterile saline solution as a cleansing agent for fixation element-skin interfaces in people.13 Cytotoxicity to canine fibroblasts has been documented when povidone-iodine concentrations exceed 0 ...
Get Price1986-7-1 · Three concentrations of povidone‐iodine (0.1% w/v, 0.2% w/v, 0.5% w/v) and one concentration of chlorhexidine (0.5% w/v) were selected as antimicrobial joint lavage solutions. Through‐and‐through joint lavage was performed with one of these antimicrobial solutions on a tarsocrural joint of 12 horses. The contralateral tarsocrural joints (control limbs) were lavaged with a …
Get Price2017-3-7 · Ringer's solution and hypochlorous acid/sodium hypochlorite showed significantly (P < 0·05) lower rates than those treated with sterile water, with a bacterial count of 6·78 ± 0·53 and 6·75 ± 0·40 log CFU/g, respectively. Sterile water-treated wounds showed a higher bacterial count, 7·61 ± 0·54 log CFU/g, on day 6, compared to ...
Get Price2017-10-24 · Clinicians use several combinations of disinfectants such as hypochlorite or hydrogen peroxide and even oral or parental administration of antibiotics to reduce bacterial growth on the wound areas in animals [].Later on, povidone-iodine (betadine), an iodine complex was used to inhibit bacterial growth routinely [].Clinical studies were carried out to know the efficiency level between povidone ...
Get Price2021-3-1 · animals were male white rat Wistar strains weighing 150-250 grams, aged 8-12 weeks divided into 4 groups. Negative control group without treatment. P1 group that is incised and treated by 10% Povidone Iodine with doses 0,5 ml. P2 group that incised and treated by Ag (silver) solution
Get Price2009-10-8 · animals had free access to pelleted food and waterad libitum. Temperature was maintained at 23± 1oC. Treatment Animals were wounded under light ether anesthesia, semiaseptically. The animals were assigned into five group (n=6). Group I was untreated group, this was taken as control. Group II animals were received Povidone iodine ointment ...
Get Price2011-4-19 · The Healing Power of Potassium Iodide (SSKI) Iodine is a halogen, related to bromine, chlorine and fluorine, all of which are essential for human life to exist. (There is some question about the essentiality of fluorine despite the benefits for teeth). The requirement for iodine ranges from 100 to 200 mcg daily, with individual variation due to ...
Get PricePovidone-iodine caused peritonitis with neutrophilic leukocytosis and a minimal left shift at the dosage rate of 3.5 ml/kg body weight. A dosage rate of 2 ml/kg only caused slight neutrophilic leukocytosis. There was a significant increase in the levels of creatinine (p=0.049) and BUN (p=0.020) in dogs that received the higher dose rate. Two dogs died from povidone-iodine toxicity with a ...
Get Price2017-3-28 · The good news is that iodine is a great antifungal. When it is directly applied directly to a mold (fungus) growing on your skin, nails, and teeth, it will kill the mold and bacteria often within 90 seconds and prevent further growth. It will also kill mold in your body if you take it internally.
Get PriceA topical povidone-iodine solution was employed in a phase 2 trial for the treatment of cancer therapy-related paronychia—an acute nail infection caused by targeted and cytotoxic remedies. Twice daily application of 2% PVP-I solution had a positive effect on clinical outcomes and quality of life [ 80 ].
Get PriceA dressing coated with AgNPs solution (0.04 mg/cm 2) was topically applied to the wound bed in the AgNPs group. 15 In the povidone-iodine group, the rats were treated by topical application of povidone-iodine solution. Wound bed in the control group was covered with a normal saline-coated dressing.
Get Price2017-3-7 · Ringer's solution and hypochlorous acid/sodium hypochlorite showed significantly (P < 0·05) lower rates than those treated with sterile water, with a bacterial count of 6·78 ± 0·53 and 6·75 ± 0·40 log CFU/g, respectively. Sterile water-treated wounds showed a higher bacterial count, 7·61 ± 0·54 log CFU/g, on day 6, compared to ...
Get Price2017-10-26 · Lugol’s solution and other preparations containing iodide have for almost a century been used as an adjuvant treatment in patients with Graves’ disease planned for thyroidectomy. Iodide has been shown to decrease thyroid hormone levels and reduce blood flow within the thyroid gland. An escape phenomenon has been feared as the iodide effect has been claimed to only be temporary.
Get PriceABSTRACT. PURPOSE: To evaluate the effectiveness of the use of the povidone-iodine (PVI) added to the liquid of wash of the peritoneal cavity in the reduction of bacterial absorption and in the remainder non-phagocyted bacteria in the circulating blood of rat. METHODS: Thirty four Wistar females rats were used, distributed in the following groups: A (n=10), non-treated; B (n=9), wash of the ...
Get PriceThe povidone-iodine is used in therapeutically effective amounts ranging up to about 25% by weight of the polymeric film, and preferably in amounts ranging from about 0.01 to 10% by weight of the polymeric film. Povidone-iodine is known to kill gram-positive and gram-negative bacteria, as wells as fungi, viruses, protozoa, and yeast.
Get Price2015-9-5 · growth.' A commonly used antimicrobial agent is povidone-iodine (Beta- [email protected]*), a complex of iodine, the bactericidal component, with polyvinylpyr- rolidone (povidone), a synthetic polymer.' The most common commercial form is a 10% solution in water yielding 1% available iodine.' Povidone-iodine
Get Price2007-8-7 · The topical application of a mixture of sugar and povidone-iodine (PI) has been reported to accelerate the healing of cutaneous wounds and ulcers by promoting reepithelialization and granulation tissue formation, as well as by having an anti-microbial effect. In order to clarify the efficacy of a 70% sugar and 3% PI paste (U-PASTA™)(SP) on infectious skin ulcers, we made a bacterial ...
Get Price2017-6-4 · Povidone Iodine solution is a relatively safe treatment for minor acute wounds. Povidone Iodine is used in the treatment of wounds but can cause dermatitis contact on the skin, have toksikogenik effects on fibroblasts and leukocyte, inhibits migration of neutrophils and monocytes decrease8. A better alternative treatment for
Get Price2021-7-15 · In animals 0.05% molecular iodine (I2) supplementation lessened symptoms of benign prostatic hyperplasia. 59 In men with BPH, 5 mg daily of Lugol's solution improved urine flow and reduced PSA values over an 8 month period. 60 In one study, NIS was found in 52% of prostate adenocarcinomas and was associated with greater aggressiveness of tumors ...
Get PriceThe invention relates to a polyketone iodine eyedrops, and relative production, wherein it adds polyketone iodine into osmotic pressure adjuster, stabilizer, and pH adjuster to be dissolved, and using pH adjuster to realize constant volume; pH adjuster at 100 volume units contain 0.1-0.5 units of polyketone iodine, 0.35-0.65 osmotic pressure adjuster mass units, stabilizer at 0.05 mass units ...
Get Price2017-3-28 · The good news is that iodine is a great antifungal. When it is directly applied directly to a mold (fungus) growing on your skin, nails, and teeth, it will kill the mold and bacteria often within 90 seconds and prevent further growth. It will also kill mold in your body if you take it internally.
Get Price2019-6-6 · which animals are being transported contains access to food or water. This law goes virtually unenforced, failing to protect farmed animals from the stresses of long transport. The Humane Methods of Slaughter Act Requires that animals be stunned into unconsciousness before slaughter, and treated humanely while on slaughterhouse premises.
Get PriceThe povidone-iodine is used in therapeutically effective amounts ranging up to about 25% by weight of the polymeric film, and preferably in amounts ranging from about 0.01 to 10% by weight of the polymeric film. Povidone-iodine is known to kill gram-positive and gram-negative bacteria, as wells as fungi, viruses, protozoa, and yeast.
Get Price2021-6-28 · Toll-Free: 1-888-726-7535. Fax: 203-588-6254. Website: www.purduepharma.com. Every effort has been made to ensure the accuracy of the Betadine Solution information published above. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the US product label or package insert.
Get PriceABSTRACT. PURPOSE: To evaluate the effectiveness of the use of the povidone-iodine (PVI) added to the liquid of wash of the peritoneal cavity in the reduction of bacterial absorption and in the remainder non-phagocyted bacteria in the circulating blood of rat. METHODS: Thirty four Wistar females rats were used, distributed in the following groups: A (n=10), non-treated; B (n=9), wash of the ...
Get Price2013-1-4 · mare was subsequently treated for 5 days during estrus by uterine lavage (sterile saline plus povidone-iodine solution) and daily intra-uterine administration of two antifungal agents (miconazole and nystatin) determined by sensitivity testing to be effective against this specific Candida organism. The mare eventually ovulated
Get Price2017-3-28 · The good news is that iodine is a great antifungal. When it is directly applied directly to a mold (fungus) growing on your skin, nails, and teeth, it will kill the mold and bacteria often within 90 seconds and prevent further growth. It will also kill mold in your body if you take it internally.
Get Price2017-6-4 · Povidone Iodine solution is a relatively safe treatment for minor acute wounds. Povidone Iodine is used in the treatment of wounds but can cause dermatitis contact on the skin, have toksikogenik effects on fibroblasts and leukocyte, inhibits migration of neutrophils and monocytes decrease8. A better alternative treatment for
Get Price2016-4-18 · A solution of approximately 0.9 percent sodium chloride (isotonic saline) has been shown to reduce infection rates in human emergency rooms, as has 1 percent povidone-iodine solutions. Even so, isotonic solution is acidic, and a polyionic solution such as lactated Ringer’s solution arguably would be even better. Hypertonic saline solution (20 ...
Get Price2014-5-19 · Application of Povidone-Iodine in Neurosurgery. J Hosp Infect 6 Suppl A:123-125. 18. Yamamoto M, Jimbo M, Tanaka N, Umebara Y, Hagiwara S. 1992. Postoperative Neurosurgical Infection and Antibiotic Prophylaxis. Neurol Med Chir (Tokyo) 32(2):72-79.
Get Price2015-9-5 · growth.' A commonly used antimicrobial agent is povidone-iodine (Beta- [email protected]*), a complex of iodine, the bactericidal component, with polyvinylpyr- rolidone (povidone), a synthetic polymer.' The most common commercial form is a 10% solution in water yielding 1% available iodine.' Povidone-iodine
Get Price2013-12-24 · lin pellets were immersed briefly in 2% povidone-iodine solution before being implanted subcutaneously using a 12-gauge trocar while under anesthesia. Insulin pellets were supplied to the mice to maintain blood glucose values around 200 mg/dL. Blood glucose values were monitored a minimum of twice a week to ensure eugly- cemia.
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