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    2012-1-1 · Abstract. Doxycycline is a tetracycline antibiotic with a potent antibacterial activity against a wide variety of bacteria. However, poor cellular penetration limits its use for the treatment of infectious disease caused by intracellular pathogens. One potential strategy to overcome this problem is the use of nanotechnology that can help to ...

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    2019-9-1 · 1. Introduction. Antibiotics have gained great attention and widely applied in all aspects of human life against infectious diseases. Thereinto, tetracycline antibiotics include tetracycline (TC), chlortetracycline (CTC), oxytetracycline (OTC) and doxycycline (DXC) are most widely used in the world against infectious diseases , .However, the extensive use of these antibiotics caused long-term ...

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