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a novel topical 2 povidoneiodine solution quality

  • A Novel Topical 2% Povidone-Iodine Solution for the ...

    Methods: Twenty-one patients aged 8 years and older were enrolled in this single-center, randomized, double-blind, vehicle-controlled Phase II clinical trial to assess the efficacy, safety and tolerability of twice-daily application of a novel 2% topical povidone-iodine solution in a dimethyl sulfoxide vehicle for 12 weeks duration. Patients were block randomized into two groups consisting of 14 patients in the active …

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  • A Novel Topical 2% Povidone-Iodine Solution for the ...

    2015-11-3 · Twenty-one patients aged 8 years and older were enrolled in this single-center, randomized, double-blind, vehicle-controlled Phase II clinical trial to assess the efficacy, safety and tolerability of twice-daily application of a novel 2% topical povidone-iodine solution in a dimethyl sulfoxide …

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  • A Novel Topical 2% Povidone-Iodine Solution for the ...

    2016-1-1 · We describe here the results of a small, randomized, double-blind, vehicle-controlled Phase II clinical trial with a novel topical agent for the treatment of common warts.Twenty-one patients aged 8 years and older were enrolled in this single-center, randomized, double-blind, vehicle-controlled Phase II clinical trial to assess the efficacy, safety and tolerability of twice-daily application of a novel 2% topical povidone-iodine solution in a dimethyl sulfoxide …

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  • [PDF] Commentary: A Novel Topical 2% Povidone

    In “A Novel Topical 2% Povidone-Iodine Solution for the Treatment of Common Warts: A Randomized, Double-Blind, Vehicle-Controlled Trial,” twenty-one patients aged 8 years and older were enrolled in Phase II clinical trial to assess the efficacy, safety, and tolerability of twice-daily application of a novel 2% topical povidone–iodine solution in a dimethyl sulfoxide vehicle for 12 weeks duration1.

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  • A randomized phase 2 trial of the efficacy and safety

    2019-6-26 · Patients were randomized to one of three treatment arms administered twice daily: 1% PVP-I (Cohort A), 2% PVP-I (Cohort B), or vehicle-control (Cohort C). The primary endpoint was a two-grade reduction (or reduction to grade 0 if involved nails were grade 1) on the six-point Paronychia Severity Grading (PSG) scale.

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  • Chemotherapy-associated paronychia treated with 2% ...

    Each patient was prescribed a topical solution comprised of 2% povidone-iodine in a dimethylsulfoxide vehicle that was prepared by a licensed compounding pharmacy. Patients were seen at 3 week and 6 week follow-up visits. Results: All 9/9 patients demonstrated complete or partial resolution. The number of nails involved for each patient ranged from 4-12.

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  • Efficacy and safety of a novel herbal solution for the ...

    The findings established that the topical herbal solution has significant influence on patients with AGA and improvement of their quality of life. This solution can be considered a significant step towards the prevention and treatment of AGA. clinicaltrials.gov Identifier: NCT03753113.

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  • Evaluation of a novel anti-aging topical formulation ...

    Background/objective: This study investigates the efficacy, tolerance, and usability of a single product containing cycloastragenol, growth factors, peptides, and antioxidants to decrease the visible signs of aging, including fine lines, and wrinkles, texture, pore size, elasticity, skin color/clarity, redness, hydration, and overall skin quality.

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  • Centaur Pharma launches novel topical solution

    2020-10-8 · Dr Dirk Kaiser, the co-innovator of WOXheal® and the Chief Scientific Officer of CytoTools AG, Germany said “WOXheal® is a novel drug born out …

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  • International www.clinpharmacol.com Journal of

    2015-12-17 · and 2 subjects received the vehicle in double blind fashion. The topical solution (P-3074 or the vehicle) was applied to the subjects’ shaven scalp o.d., in the morning, for 7 days.

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  • Chemotherapy-associated paronychia treated with

    2017-6-26 · Each patient was prescribed a topical solution comprised of 2% povidone–iodine (PVP-I) in a dimethylsulfoxide (DMSO) vehicle that was prepared by a licensed compounding pharmacy. The patient was instructed to apply the solution twice daily to the nail folds, nail plate, and subungual space.

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  • Chemotherapy-associated paronychia treated with

    2017-6-26 · Each patient was prescribed a topical solution comprised of 2% povidone-iodine in a dimethylsulfoxide vehicle that was prepared by a licensed compounding pharmacy. Patients were seen at 3 week and 6 week follow-up visits.All 9/9 patients demonstrated complete or partial resolution.

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  • Targeting Reactive Oxygen Species Production as a

    2020-6-19 · Currently topical solutions of NAC are already used in ophthalmology for application in keratoconjunctivitis sicca (using 20% weight/volume solution or 10%), meibomian gland dysfunction (using 5%) and Sjögren's dry eye syndrome (also using 5%). This is a single center, double-blind, placebo-controlled, randomized trial.

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  • A Multicenter, Randomized, Placebo-Controlled,

    Background: An alternative to currently marketed topical minoxidil solutions is desirable. Objective: To assess the efficacy and safety of a new 5% minoxidil topical formulation in a propylene glycol-free foam vehicle in men with androgenetic alopecia (AGA). Methods: This was a 16-week, double-blind, placebo-controlled trial of 5% minoxidil topical foam (MTF) in 352 men, 18 to 49 years old.

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  • Efficacy and safety of a novel herbal solution for the ...

    2020-10-28 · The present study set to evaluate the effectiveness and safety of the topical herbal solution and to compare it with 5% minoxidil in men with AGA. A randomized, double-blind controlled trial was conducted from 28 November 2018 to 2 September 2019, in Sina Hospital, Tabriz, Iran. 24 healthy males (mean [SD] age 33.04 [5.81]) with mild to ...

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  • A Novel Multi-Ingredient Supplement Reduces

    2021-6-15 · Dry eye is a multifactorial condition of the eye caused by insufficient tear production and imbalance in tear composition leading to faster evaporation of tear fluid. It is also associated with inflammation that often leads to ocular surface damage. Symptoms of dry eyes include itchiness, soreness, red eyes, a burning sensation, eye fatigue and blurred vision.

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  • Topical antimicrobial agents for treating foot ulcers

    2017-6-14 · It is unclear whether use of a non‐dressing antimicrobial topical treatment compared with non‐dressing non‐antimicrobial treatment affects the resolution of infection over a medium‐term follow‐up period: RR 1.16, 95% CI 0.54 to 2.51 (low‐certainty evidence ‐ downgraded twice for imprecision) Analysis 2.2.

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  • Perception and quality of life associated with the

    This 28-d, open-label, multicenter, single-arm clinical study was designed to evaluate perceptions of olopatadine 0.2% in patients with active ocular allergic signs and symptoms. The study enrolled 330 patients, 5 to 94 y of age, who had previously used olopatadine 0.1% for active allergic conjunctivitis. Most patients were white (n=230; 70.1%) and female (n=239; 72.9%). Of all enrolled ...

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  • A Novel Synergistic Pharmaceutical Composition

    A novel synergistic pharmaceutical composition for preparation of topical formulations for prophylaxis and treatment of wounds, burn wounds, skin grafts, pressure ulcers and diabetic foot ulcers is disclosed. The synergistic composition comprises a mitogenic protein in combination with one or more bactericidal and bacteriostatic agents.

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  • Electrospinning: A novel nano-encapsulation

    2017-12-1 · Electrospinning is a novel delivery approach for bioactive compounds, it opens a new horizon in food technology with the possibility of commercialization in the near future. This paper presents a brief summary of electrospinning, and its application in encapsulation different types of bioactive compounds by biopolymer matrixes are also highlighted.

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  • Chemotherapy-associated paronychia treated with 2% ...

    2017-6-26 · Each patient was prescribed a topical solution comprised of 2% povidone-iodine in a dimethylsulfoxide vehicle that was prepared by a licensed compounding pharmacy. Patients were seen at 3 week and 6 week follow-up visits.All 9/9 patients demonstrated complete or partial resolution.

    Get Price
  • Targeting Reactive Oxygen Species Production as a

    2020-6-19 · Currently topical solutions of NAC are already used in ophthalmology for application in keratoconjunctivitis sicca (using 20% weight/volume solution or 10%), meibomian gland dysfunction (using 5%) and Sjögren's dry eye syndrome (also using 5%). This is a single center, double-blind, placebo-controlled, randomized trial.

    Get Price
  • A Systematic Review of Topical Finasteride in the ...

    2018-4-1 · A novel combination topical treatment by the name NuH Hair [topical FNS, dutasteride and minoxidil (MNX)], was formulated by Rafi and Katz (2011). 15 male patients were asked to apply the solution daily for nine months and were given the option of adding three further components to their treatment protocol: 1) oral FNS 1 mg daily 2) topical MNX ...

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  • A Novel Multi-Ingredient Supplement Reduces

    2021-6-15 · Dry eye is a multifactorial condition of the eye caused by insufficient tear production and imbalance in tear composition leading to faster evaporation of tear fluid. It is also associated with inflammation that often leads to ocular surface damage. Symptoms of dry eyes include itchiness, soreness, red eyes, a burning sensation, eye fatigue and blurred vision.

    Get Price
  • Topical antimicrobial agents for treating foot ulcers in ...

    2017-6-14 · It is unclear whether use of a non‐dressing antimicrobial topical treatment compared with non‐dressing non‐antimicrobial treatment affects the resolution of infection over a medium‐term follow‐up period: RR 1.16, 95% CI 0.54 to 2.51 (low‐certainty evidence ‐ downgraded twice for imprecision) Analysis 2.2.

    Get Price
  • A Novel Synergistic Pharmaceutical Composition For

    A novel synergistic pharmaceutical composition for preparation of topical formulations for prophylaxis and treatment of wounds, burn wounds, skin grafts, pressure ulcers and diabetic foot ulcers is disclosed. The synergistic composition comprises a mitogenic protein in combination with one or more bactericidal and bacteriostatic agents.

    Get Price
  • Centaur Pharma launches novel topical solution

    2020-10-8 · Centaur Pharma launches novel topical solution WoxHeal for the treatment of Diabetic Foot Ulcer (Eds: Disclaimer: The following content is a press release. ... they not only hamper the Quality of ...

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  • Effects of a New Topical Treatment Containing Several

    2018-10-10 · Spectral. DNC-N® (DS Laboratories, Inc.) is a topical solution containing numerous hair growth promoters, including pyrrolidinyl diaminopyrimidine oxide, azelaic acid, lysophosphatidic acid, copper tripeptide-1, myristoyl pentapeptide-17, adenosine, piroctone olamine, retinol, and caffeine, in a novel nanosomal delivery system.

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  • Perception and quality of life associated with the use

    This 28-d, open-label, multicenter, single-arm clinical study was designed to evaluate perceptions of olopatadine 0.2% in patients with active ocular allergic signs and symptoms. The study enrolled 330 patients, 5 to 94 y of age, who had previously used olopatadine 0.1% for active allergic conjunctivitis. Most patients were white (n=230; 70.1%) and female (n=239; 72.9%). Of all enrolled ...

    Get Price
  • Electrospinning: A novel nano-encapsulation

    2017-12-1 · Electrospinning is a novel delivery approach for bioactive compounds, it opens a new horizon in food technology with the possibility of commercialization in the near future. This paper presents a brief summary of electrospinning, and its application in encapsulation different types of bioactive compounds by biopolymer matrixes are also highlighted.

    Get Price
  • Targeting Reactive Oxygen Species Production as a

    2020-6-19 · Currently topical solutions of NAC are already used in ophthalmology for application in keratoconjunctivitis sicca (using 20% weight/volume solution or 10%), meibomian gland dysfunction (using 5%) and Sjögren's dry eye syndrome (also using 5%). This is a single center, double-blind, placebo-controlled, randomized trial.

    Get Price
  • Topical antimicrobial agents for treating foot ulcers

    2017-6-14 · It is unclear whether use of a non‐dressing antimicrobial topical treatment compared with non‐dressing non‐antimicrobial treatment affects the resolution of infection over a medium‐term follow‐up period: RR 1.16, 95% CI 0.54 to 2.51 (low‐certainty evidence ‐ downgraded twice for imprecision) Analysis 2.2.

    Get Price
  • Efficacy of Dilute Povidone-Iodine against Multi-

    2018-2-11 · To study the in vitro effect of novel low-dose povidoneiodine formulations against established biofilms of multi-drug resistant Staphylococcus aureus, Klebsiella pneumoniae, Pseudomonas aeruginosa and Candida albicans and to test the Minimal Inhibitory Concentration of the same formulations against Candida auris, Trichophton mentagrophytes, Microsporum canis, Candida albicans and Aspergillus ...

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  • A Systematic Review of Topical Finasteride in the ...

    2018-4-1 · A novel combination topical treatment by the name NuH Hair [topical FNS, dutasteride and minoxidil (MNX)], was formulated by Rafi and Katz (2011). 15 male patients were asked to apply the solution daily for nine months and were given the option of adding three further components to their treatment protocol: 1) oral FNS 1 mg daily 2) topical MNX ...

    Get Price
  • Centaur Pharma launches novel topical solution

    2020-10-8 · Centaur Pharma launches novel topical solution WoxHeal for the treatment of Diabetic Foot Ulcer (Eds: Disclaimer: The following content is a press release. ... they not only hamper the Quality of ...

    Get Price
  • Topical retinoids in acne – an evidence‐based

    2008-11-25 · An early trial in 1978 reported that a twice daily application of 2 % erythro-mycin base in hydroalcoholic solution accompanied by once daily use of 0.05 % tretinoin solution was substantially more effective than monotherapy for treatment of moderate inflammatory acne (EBM level 3b, n = 80).

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  • Formulation and clinical evaluation of silymarin

    Formulation 2 (20% pluronic and 3% lecithin) was found to be the optimal base for topical delivery of silymarin as it showed optimum pH, viscosity, drug content, and satisfactory in vitro silymarin permeation. The silymarin PLO formulation significantly relieved inflammatory symptoms of AD such as redness, swelling, and inflammation.

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  • Prevention of hemodialysis catheter infections:

    2018-11-8 · There was a significant reduction in CRBSI rates in the ethanol/heparin group (2.53 vs. 6.7 per 1000 catheter days (P = 0.04). 53 In a large (N = 1460 patients), multicenter, randomized controlled trial in nontunneled catheters, 60% ethanol AML was instilled for 2 minutes and removed after each HD session vs. saline lock. 54 There was no ...

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  • Coffee by-products in topical formulations: A review ...

    2021-5-1 · Green coffee oil was then incorporated in topical formulations to evaluate the influence of its concentration in physical stability, in vitro SPF and in vivo protective effects. Green coffee oil content in formulations vary between 2.5 and 15%. All formulations were …

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  • Formulation and characterization of a 0.1%

    2016-7-25 · 2.3. Cream storage. The cream was packaged in 30 ml aluminum tubes (COOPER, Melun, France) and stored in a climatic chamber conforming to ICH (International Consensus on Harmonization, 2015) at 25 ± 2 °C under 60 ± 5% relative humidity.. 2.4. Sample preparation: rapamycin extraction and recovery. An aliquot of cream (2 g) was introduced into an Erlenmeyer flask with 10 ml of methanol …

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  • A Study of Efficacy of Benzoyl Peroxide Regimens in ...

    2019-6-27 · Subjects were randomly assigned either 2.5% benzoyl peroxide gel or 5% benzoyl peroxide gel for 2 weeks. Benzoyl peroxide gel in this study comprised benzoyl peroxide in a gel base. During the study, using of other topical treatment such as topical antibiotics, antiperspirant or …

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  • 203567Orig1s000 - Food and Drug Administration

    2014-7-1 · The Microbial Limits specification for Efinaconazole Topical Solution, 10% is acceptable from a Product Quality Microbiology perspective. Therefore, this submission is recommended for approval from the standpoint of product quality microbiology. Efinaconazole Topical Solution, 10% is for administrationdirectly to the nail, to the skin folds

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  • Article - JDDonline - Journal of Drugs in Dermatology

    2021-1-19 · The neck plays a telling role as an age indicator. Due to its anatomy and function, neck skin ages differently than facial skin and special considerations need to be taken when providing treatment. A randomized, double-blind, regimen-controlled study was conducted to assess the efficacy and tolerability of a novel topical cosmetic cream (NCC) specifically tailored to address the signs of skin ...

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  • Tea Tree Oil: A Novel Approach to MRSA –

    2014-2-16 · In the United States, community acquired-MRSA (CA-MRSA) infections, alone, impose an annual burden of 478 million to 2.2 billion on third-party payers, and an estimated 1.4 to 13.8 billion on society. 5. Drug companies and researchers are scrambling to design and test different synthetic drugs to battle antibiotic-resistant organisms such ...

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  • Povidone-iodine solution as SARS-CoV-2 prophylaxis for ...

    2020-10-27 · Povidone-iodine solution as SARS-CoV-2 prophylaxis for procedures of the upper aerodigestive tract a theoretical framework ... we propose a prophylactic treatment protocol for the application of topical povidone-iodine to the upper aerodigestive tract. Conclusion: Such an approach represents a low-cost, low-morbidity measure that may reduce the ...

    Get Price
  • Topical Antifungals for Treatment of Onychomycosis -

    2016-11-1 · Elewski BE, et al. Efficacy and safety of tavaborole topical solution, 5%, a novel boron-based antifungal agent, for the treatment of toenail onychomycosis. J Am Acad Dermatol . 2015;73(1):62–69.

    Get Price
  • FPIN’s Help Desk Answers

    2016-11-1 · Topical Antifungals for Treatment of Onychomycosis ... tent findings from good-quality randomized ... cal solution, 5%, a novel boron-based antifungal agent,

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  • The Effect of Different Topical Agents (Silver ...

    2014-9-29 · It was aimed to comparatively evaluate the effects of dressing methods with silver sulfadiazine, povidone-iodine, and saline which have a common use in routine practices for burn injuries. Twenty-eight Sprague Dawley adult female rats were used in this study. All the rats were divided into 4 groups: the control group, the povidone-iodine group, the saline group, and the silver sulfadiazine group.

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  • Development of a Topical Treatment for Psoriasis

    2016-2-12 · Background Psoriasis is a chronic inflammatory skin disorder involving marked immunological changes. IL-17-targeting biologics have been successful in reducing the disease burden of psoriasis patients with moderate-to-severe disease. Unfortunately, the stratum corneum prevents penetration of large molecule weight proteins, including monoclonal antibodies.

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  • Antibacterial FANA oligonucleotides as a novel

    2021-2-2 · Souleimanian, N. et al. Antisense 2’-Deoxy-2’-Fluoro-β-D-Arabinonucleic Acid (2’F-ANA) oligonucleotides: In vitro gymnotic silencers of gene expression whose potency is …

    Get Price
  • Developing New Ways to Evaluate Bioequivalence for

    2020-10-27 · Povidone-iodine solution as SARS-CoV-2 prophylaxis for procedures of the upper aerodigestive tract a theoretical framework ... we propose a prophylactic treatment protocol for the application of topical povidone-iodine to the upper aerodigestive tract. Conclusion: Such an approach represents a low-cost, low-morbidity measure that may reduce the ...

    Get Price
  • Povidone-iodine solution as SARS-CoV-2 prophylaxis for ...

    2020-2-24 · The aim of the present work was to determine the active pharmaceutical ingredient of samples of povidoneiodine solutions 10% (topical solution and vaginal douche), which were obtained from market in Syria (A, B, C) for povidone-iodine 10% topical solution and (D, E, F) for povidone-iodine 10% vaginal douche and one solution produced by Mundipharma Company (Betadine 10% topical solution …

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  • Quality Assessment of some Povidone-Iodine

    2014-2-16 · In the United States, community acquired-MRSA (CA-MRSA) infections, alone, impose an annual burden of 478 million to 2.2 billion on third-party payers, and an estimated 1.4 to 13.8 billion on society. 5. Drug companies and researchers are scrambling to design and test different synthetic drugs to battle antibiotic-resistant organisms such ...

    Get Price
  • Tea Tree Oil: A Novel Approach to MRSA –

    2014-9-29 · It was aimed to comparatively evaluate the effects of dressing methods with silver sulfadiazine, povidone-iodine, and saline which have a common use in routine practices for burn injuries. Twenty-eight Sprague Dawley adult female rats were used in this study. All the rats were divided into 4 groups: the control group, the povidone-iodine group, the saline group, and the silver sulfadiazine group.

    Get Price
  • The Effect of Different Topical Agents (Silver ...

    2016-11-1 · Elewski BE, et al. Efficacy and safety of tavaborole topical solution, 5%, a novel boron-based antifungal agent, for the treatment of toenail onychomycosis. J Am Acad Dermatol . 2015;73(1):62–69.

    Get Price
  • Topical Antifungals for Treatment of Onychomycosis -

    2016-11-1 · Topical Antifungals for Treatment of Onychomycosis ... tent findings from good-quality randomized ... cal solution, 5%, a novel boron-based antifungal agent,

    Get Price
  • FPIN’s Help Desk Answers

    2018-3-31 · Besides, Testavan, which is a 2% testosterone gel, is under registration in Europe and already approved in Australia in May 2017. Testavan uses a novel hydroalcoholic and highly viscous topical formulation. This product comes with a metered dose dispenser and a cap applicator that allows a hands-free application for precise dispensing and ...

    Get Price
  • A new 2% testosterone gel formulation: a comparison

    2020-6-2 · Onychomycosis is the most prevalent nail condition worldwide and has a significant impact on quality of life. 1 There were 10 million physician visits for nail fungal infections in the National Ambulatory Medical Care Survey from 2007 to 2016, which was more than double the number of all other nail diagnoses combined. 2 Therefore, it is important for dermatologists to be familiar with the most ...

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  • Onychomycosis: New Developments in Diagnosis,

    2017-9-1 · Purpose: Topical administration of the anti-inflammatory agent cyclosporin A (CsA) is recommended for long-term management of dry eye syndrome (DES), yet standard ophthalmic CsA preparations have been reported to be unstable. In this trial, the efficacy and safety of Clacier™ (based on a phase 3 study developed by Huons Co. Ltd.), a novel 0.05% CsA nanoemulsion formulation, are …

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  • Evaluation of Skin Quality Improvement - Full Text

    2017-3-31 · An evaluation of the percent improvement in skin quality when the 'Onabotulinum Toxin Type A' treated side of face is compared to the 'placebo' treated side of the face. Good skin quality is defined as small pore size, evenness of skin texture, evenness of skin tone, minimal presence of wrinkles, and minimal presence of scars.

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  • Povidone-iodine solution as SARS-CoV-2 prophylaxis for ...

    2020-10-27 · Povidone-iodine solution as SARS-CoV-2 prophylaxis for procedures of the upper aerodigestive tract a theoretical framework ... we propose a prophylactic treatment protocol for the application of topical povidone-iodine to the upper aerodigestive tract. Conclusion: Such an approach represents a low-cost, low-morbidity measure that may reduce the ...

    Get Price
  • A new 2% testosterone gel formulation: a comparison

    2018-3-31 · Besides, Testavan, which is a 2% testosterone gel, is under registration in Europe and already approved in Australia in May 2017. Testavan uses a novel hydroalcoholic and highly viscous topical formulation. This product comes with a metered dose dispenser and a cap applicator that allows a hands-free application for precise dispensing and ...

    Get Price
  • Evaluation of Clinical Efficacy and Safety of a Novel ...

    2017-9-1 · Purpose: Topical administration of the anti-inflammatory agent cyclosporin A (CsA) is recommended for long-term management of dry eye syndrome (DES), yet standard ophthalmic CsA preparations have been reported to be unstable. In this trial, the efficacy and safety of Clacier™ (based on a phase 3 study developed by Huons Co. Ltd.), a novel 0.05% CsA nanoemulsion formulation, are …

    Get Price
  • Does routine topical antimicrobial administration

    2020-12-21 · The authors identified several risk factors for DSWI (including mammary artery harvesting, diabetes and peripheral vascular disease) and a protective effect of the novel closuring protocol that consisted of the aforementioned topical antibiotics as well as the usage of 6 figure-of-8 wires for sternal closure in all patients, if appropriate; and ...

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  • Antibacterial FANA oligonucleotides as a novel

    2021-2-2 · Souleimanian, N. et al. Antisense 2’-Deoxy-2’-Fluoro-β-D-Arabinonucleic Acid (2’F-ANA) oligonucleotides: In vitro gymnotic silencers of gene expression whose potency is …

    Get Price
  • Topical Delivery of Four Neuroprotective Ingredients

    2020-5-7 · Next, an ethanol solution (25% v/v) containing 2.5 mg/mL FITC and 2.5 mg/mL rhodamine B were used to prepare dye-loaded gel solution as a control for comparison. Dye-loaded ethosomes gels, a dye-loaded gel solution and a blank gel were applied topically to the human cadaver skin, placed on Franz diffusion cells in dark using the three methods ...

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  • New Herbal Biomedicines for the Topical Treatment of ...

    Herbal extracts and isolated plant compounds play an increasing role in the treatment of skin disorders and wounds. Several new herbal drugs, medicinal products and cosmetic products for the treatment of various skin conditions have been developed in recent years. In this nonsystematic review, we focus on herbal drugs that were tested in controlled clinical studies or in scientifically sound ...

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  • Hormone therapy as a possible solution for

    2020-9-28 · Nocturia, waking to pass urine during the main sleeping period, 1 is a common problem in older women as it tends to increase after menopause. 2-5 In the global population, nocturia has a multifactorial etiology, but is mostly the result of nocturnal polyuria. 6,7 The lack of endogenous estrogen in this postmenopausal population can influence the onset of nocturia through bladder dysfunction, 4 ...

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  • Topical and Transdermal Drug Products - USP-NF

    2017-5-9 · Topical Solutions Topical solutions are liquid preparations, that usually are aqueous but often contain other solvents such as al-cohol and polyols that contain one or more dissolved chemical substances intended for topical application to the skin, or, as in the case of Lidocaine Oral Topical Solu-tion USP, to the oral mucosal surface.

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  • Developing New Ways to Evaluate Bioequivalence for

    2020-6-10 · Povidone-iodine (PVP-I) has been suggested as a topical solution. PVP-I works by releasing free iodine, which disrupts microbial metabolic pathways, destabilizes structural components of cell membranes, and leads to irreversible damage to pathogens. 15 It is a potent virucidal via inhibition of N1, N2, and N3 neuraminidase as well as inhibition ...

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  • Povidone-Iodine Use in Sinonasal and Oral Cavities: A ...

    2020-2-24 · The aim of the present work was to determine the active pharmaceutical ingredient of samples of povidoneiodine solutions 10% (topical solution and vaginal douche), which were obtained from market in Syria (A, B, C) for povidone-iodine 10% topical solution and (D, E, F) for povidone-iodine 10% vaginal douche and one solution produced by Mundipharma Company (Betadine 10% topical solution …

    Get Price
  • Quality Assessment of some Povidone-Iodine

    Because the symptoms of adenoviral conjunctivitis may be severe, investigators have explored other treatment options for patients with symptomatic disease including a topical combination of dexamethasone 0.1% and povidoneiodine 0.4%.4 This novel formulation was compared with cidofovir 0.5%, a combination tobramycin-dexamethasone ophthalmic ...

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  • CRSTEurope | Pros and Cons of Topical Steroids for

    2018-3-31 · Besides, Testavan, which is a 2% testosterone gel, is under registration in Europe and already approved in Australia in May 2017. Testavan uses a novel hydroalcoholic and highly viscous topical formulation. This product comes with a metered dose dispenser and a cap applicator that allows a hands-free application for precise dispensing and ...

    Get Price
  • A new 2% testosterone gel formulation: a comparison

    2019-11-27 · The topical delivery of drugs to the cervix for the treatment of cervical cancer is an underexplored area of research that has the potential to significantly improve therapeutic outcome. Here, we design a novel topical drug delivery system for localized delivery in the vaginal tract using intravaginal silicone rings loaded with Alisertib.

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  • Development of an intravaginal ring for the topical ...

    2021-2-17 · A novel topical minocycline foam for the treatment of moderate-to-severe acne vulgaris: Results of 2 randomized, double-blind, phase 3 studies. J Am Acad Dermatol 2019; 80:168. Raoof TJ, Hooper D, Moore A, et al. Efficacy and safety of a novel topical minocycline foam for the treatment of moderate to severe acne vulgaris: A phase 3 study.

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  • Efficacy and Safety of Topical Rapamycin in Patients

    2021-7-15 · Objectives In recent years, various formulations containing rapamycin, mainly petrolatum-based, have been tested on facial angiofibromas in tuberous sclerosis. They are often poorly tolerated due to irritation and bleeding. In addition, their effectiveness was insufficient in young adults. The objective of this study was to develop and characterise a hydro-alcoholic gel containing solubilised ...

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  • Povidone-iodine: Uses, Interactions, Mechanism of

    Povidone iodine gel is a gynecological topical semi-mobile colloidal agent made by povidone iodine and hydrophilic matrix. It is a system for maintaining its sustained release. Owing to the continuous release of free iodine, it can enable the skin and mucous membranes to maintain a certain effective concentration of iodine for killing bacteria.

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  • Topical Antifungals for Treatment of Onychomycosis -

    2016-11-1 · Elewski BE, et al. Efficacy and safety of tavaborole topical solution, 5%, a novel boron-based antifungal agent, for the treatment of toenail onychomycosis. J Am Acad Dermatol . 2015;73(1):62–69.

    Get Price
  • A new 2% testosterone gel formulation: a comparison

    2018-3-31 · Besides, Testavan, which is a 2% testosterone gel, is under registration in Europe and already approved in Australia in May 2017. Testavan uses a novel hydroalcoholic and highly viscous topical formulation. This product comes with a metered dose dispenser and a cap applicator that allows a hands-free application for precise dispensing and ...

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  • Pharmaceutics | Free Full-Text | Topical Inserts: A ...

    The development of topical inserts for the prevention of sexually transmitted infections (STIs), particularly human immunodeficiency virus (HIV), represents a promising alternative to oral and parenteral pre-exposure prophylaxis (PrEP) dosage forms. They may be used for vaginal and/or rectal administration of a variety of agents with antiviral activity. Topical inserts deliver drugs to the ...

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  • About Ultravate® Lotion - Ultravate

    ULTRAVATE (halobetasol propionate) Lotion is a corticosteroid indicated for the topical treatment of plaque psoriasis in patients 12 years of age and older. Usage: Limit use to 50 g/week. Discontinue treatment when control is achieved. If no improvement is seen within 2 weeks, reassess diagnosis.

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  • Menlo Therapeutics Receives FDA Approval of ZILXI™

    2020-1-7 · ZILXI, developed as FMX103 by Menlo’s wholly-owned subsidiary Foamix Pharmaceuticals Ltd. (“Foamix”), is the first minocycline product of any kind to be approved by the FDA for use in ...

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  • JBJI - Pursuit of the ideal antiseptic irrigation solution ...

    2021-5-26 · Although high-quality clinical trials exploring surfactant irrigation in PJI management are scarce, the Center for Disease Control (CDC), World Health Organization (WHO), National Institute for Health and Care Excellence (NICE), and 2018 international consensus meeting (ICM) on musculoskeletal infections recommend against the use of antibiotic irrigation in PJI and SSI prevention and treatment ...

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  • Hyaluronan Hybrid Cooperative Complexes as a Novel ...

    2016-10-10 · Indeed, when the η 0 of the sample 2 (mix of the H-HA chains and the low HA chains at room temperature), was compared to the η 0 of the sample 4 (the two same solutions undergoing the thermal treatment, and mixed after), only a 4.7 fold viscosity decrease was observed while a 3.2-fold decrease in viscosity was observed with the sample 1 (H-HA).

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  • Is Topical Ketamine Ready For Prime Time?

    2019-7-3 · According to the etch-pattern scale, enamel etching with 37% PA gel resulted in roughened surfaces featuring typical honeycomb and cobblestone etch patterns, i.e. types 1, 2 respectively, in ...

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